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ea0032p799 | Paediatric endocrinology | ECE2013

Urinary phthalates from 168 girls and boys measured twice a year during a 5-year period: associations with adrenal androgen levels and puberty

Mouritsen Annette , Frederiksen Hanne , Sorensen Kaspar , Aksglaede Lise , Hagen Casper , Erik Niels , Erik Skakkebaek , M Main Katharina , Andersson Anna-Maria , Juul Anders

Background: Little is known about the possible deleterious effects of phthalate exposure on endogenous sex steroid levels in childrenDesign: A longitudinal study.Materials and methods: 168 Healthy children (84 girls) were examined every 6 months for 5 years, with pubertal staging, measurements of serum levels of DHEAS and Δ4-androstenedione (Adione) and repetitive longitudinal morning urinary measurements of 14 phthalate metab...

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Urinary phthalates from 168 girls and boys measured twice a year during a 5-year period: associations with adrenal androgen levels and puberty

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